What is shotgun sequencing?

This video shows how shotgun sequencing works. http://www.bimatics.blogspot.com In shotgun sequencing many copies of the entire genome are blown up into millions of small fragments. Each small fragment is sequenced. Powerful computers then assemble the individual fragments into the original configuration. Repeat sequences pose a problem for this approach because their sizes can be much larger than the small fragments.

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Channels: Genetics

Tags: Shotgun sequencing

Uploaded by: ( Send Message ) on 11-10-2012.

Duration: 0m 59s