T Cell Development Animation

This video describes the process of T cell development. All T cells originate from haematopoietic stem cells in the bone marrow. Haematopoietic progenitors derived from haematopoietic stem cells populate the thymus and expand by cell division to generate a large population of immature thymocytes. The earliest thymocytes express neither CD4 nor CD8, and are therefore classed as double-negative cells. As they progress through their development they become double-positive thymocytes (CD4plus CD8plus), and finally mature to single-positive (CD4plus CD8minus or CD4minus CD8plus) thymocytes that are then released from the thymus to peripheral tissues.

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Channels: Microbiology

Tags: immunology cell biology development cells medical

Uploaded by: ( Send Message ) on 27-05-2009.

Duration: 2m 41s