This In3D animation highlights the inital steps of RNA transscription by the RNA-dependent RNA polymerase from reovirus. In this animation you will observe several stages of transcription initiation. Beginning with a quick orientation of the enzyme itself, the viewer is then shown the capped RNA template that will later be used for initiation of transcription. The capped RNA binds in a special cleft on the enxyme surface. Following binding, the 3'-end of the RNA is fed into the enzyme actve site, where stranscription initiation occurs. Transcription begins with the formation of a pppGpG dimer (shown). Following formation of the dimer elongation comenses ielding full length RNA of the opposite polarity. www.scianafilms.com
Channels: Scientific Animations Microbiology
Tags: reovirus
Uploaded by: sertan ( Send Message ) on 05-01-2008.
Duration: 1m 59s