Link between Aging and Cancer

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Buck Institute CEO Brian Kennedy, PhD, in conversation with Buck faculty Judith Campisi, PhD. Campisi is internationally-recognized for her research on the link between cancer and aging. She is considered a pioneer in the field of senescence, which occurs when cells stop dividing in response to DNA damage. Cellular senescence acts as a tumor suppressor but also drives the aging process. Judith Campisi has received international recognition for her contributions to understanding why age is the largest single risk factor for developing a panoply of diseases, ranging from neurodegeneration to cancer. Her highly acclaimed research integrates the genetic, environmental and evolutionary forces that result in aging and age-related diseases, and identifies pathways that can be modified to mitigate basic aging processes.