"Lec 10 - Biomolecular Engineering: Engineering of Immunity (cont.)"Frontiers of Biomedical Engineering (BENG 100) Professor Saltzman continues his presentation on the topic of vaccine. First, Professor Saltzman describes the host immune response to pathogen recognition, in terms of immunoglobulin release, T-cell activation, and memory cell production. The production, distribution, and challenges involved in making of the Salk polio vaccine and the modern, oral polio vaccine are discussed. Professor Saltzman then talks about the range of bioengineering approaches that can be used to produce vaccine: attenuated, subunit, and DNA-based. Finally, a life-intervention cost analysis (cost of technology per human life saved) for vaccine was compared to other policies to further emphasize the impact of vaccine on improving public health worldwide. 00:00 - Chapter 1. Mechanism of Vaccination 10:40 - Chapter 2. Boosters and Antibodies 18:54 - Chapter 3. History of the Polio Vaccine 35:01 - Chapter 4. Molecular, Clinical, and Economic Limitations of Vaccination Complete course materials are available at the Open Yale Courses website: http://open.yale.edu/courses This course was recorded in Spring 2008.
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Tags: attenuated DNA vaccine immunoglobulin infectious disease Jonas Salk polio subunit
Uploaded by: yalefrontbio ( Send Message ) on 31-08-2012.
Duration: 52m 50s
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Lec 1 - What Is Biomedical Engineering?
Lec 2 - What Is Biomedical Engineering? (cont.)
Lec 4 - Genetic Engineering (cont.)
Lec 5 - Cell Culture Engineering
Lec 6 - Cell Culture Engineering (cont.)
Lec 7 - Cell Communication and Immunology
Lec 8 - Cell Communication and Immunology (cont.)
Lec 9 - Biomolecular Engineering: Engineering of Immunity
Lec 11 - Biomolecular Engineering: General Concepts
Lec 12 - Biomolecular Engineering: General Concepts (cont.)
Lec 13 - Cardiovascular Physiology
Lec 14 - Cardiovascular Physiology (cont.)
Lec 15 - Cardiovascular Physiology (cont.)
Lec 17 - Renal Physiology (cont.)
Lec 18 - Biomechanics and Orthopedics
Lec 19 - Biomechanics and Orthopedics (cont.)
Lec 23 - Tissue Engineering (cont.)