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Actin Polymerization

Actin Polymerization. Actin polymerization and depolymerization is necessary in chemotaxis and cytokinesis. Nucleating factors are necessary to stimulate actin polymerization. One such nucleating factor is the ARP complex which acts as a barbed end of actin in its shape to stimulate the nucleation of G-actin (or monomeric actin). The ARP complex can also bind to actin filaments at 70 degrees to form new actin branches off of existing actin filaments. Also, actin filaments themselves bind ATP, and hydrolysis of this ATP stimulates destabilization of the polymer. Text Reff: Wikipedia

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Channels: Cell Biology Molecular Biology

Tags: actin polymerization

Uploaded by: ( Send Message ) on 26-03-2009.

Duration: 1m 10s