Pharmacology - Receptor and Antagonist

Definition of Receptor 1. In cell biology, a structure on the surface of a cell (or inside a cell) that selectively receives and binds a specific substance. There are many receptors. There is a receptor for (insulin; there is a receptor for low-density lipoproteins (LDL); etc. To take an example, the receptor for substance P, a molecule that acts as a messenger for the sensation of pain, is a unique harbor on the cell surface where substance P docks. Without this receptor, substance P cannot dock and cannot deliver its message of pain. Variant forms of nuclear hormone receptors mediate processes such as cholesterol metabolism and fatty acid production. Some hormone receptors are implicated in diseases such as diabetes and certain types of cancer. A receptor called PXR appears to jump-start the body's response to unfamiliar chemicals and may be involved in drug-drug interactions. 2. In neurology, a terminal of a sensory nerve that receives and responds to stimuli Antagonist (pharmacology) Antagonist in the body of a receptor binding to the receptor in the place of a natural compound that stimulates the receptor is stimulated as a result of naturally occurring compounds that prevent. Competition from outside the compound antagonizmada tries to connect to the natural compound with the receptor and the receptor is connected to a certain threshold and the concentration of contaminant. In one, the effect of concentration of noncompetitive antagonist, there is not even a small amount, regardless of the situation prevents the receptor.

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