This conceptual mode of action animation is of the drug Viagra developed by Pfizer pharmaceuticals.
Viagra functions by inhibiting the enzyme phosphodiesterase-5 PDE-5. Under normal conditio...(more)
This conceptual mode of action animation is of the drug Viagra developed by Pfizer pharmaceuticals.
Viagra functions by inhibiting the enzyme phosphodiesterase-5 PDE-5. Under normal conditions PDE-5 converts cyclic-GMP cGMP into GMP shown as green and red spheres.
Viagra selectively inhibits PDE-5 by blocking the site where cGMP binds. As a result, the cellular concentration of cGMP increases, causing an increase in blood flow to the corpus cavernosum.
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