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Adult Stem Cells and Regeneration
Doug Melton and Nadia Rosenthal are leaders in stem cell research, working primarily with mouse and human tissue. They will discuss where embryonic and adult stem cells come from and the biology of how they supply the cells the body needs. Stem cells are fundamental to biology. In the course of embryonic development, stem cells generate all the specialized cells that populate body tissues like muscle, the nervous system, and blood. In adults, reserves of stem cells repair and regenerate tissues damaged by disease and wounding. Because of the potential of stem cells to generate fresh, healthy cells, there is a huge interest in cultivating them to treat various diseases. This year\'s Holiday Lectures will explore exciting progress toward the goal of harnessing stem cells to treat diabetes, nerve damage, and heart disease.
Tags: stem cell Regeneration Status: protected
Created: March 16, 2009, 1:19 am

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Deconstructing Obesity Lectures
In the 2004 Holiday Lectures on Science, HHMI investigators Ronald M. Evans and Jeffrey M. Friedman discuss how the body regulates weight by carefully controlling the storage and burning of fat—and how a better understanding of these complex metabolic systems could lead researchers to treatments that curb obesity and improve public health.
Tags: obesity Status: private_owner_approval
Created: March 16, 2009, 3:49 pm

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Muscle contraction
Muscle Contraction related Videos. Wikipedia Text info: Muscle fiber generates tension through the action of actin and myosin cross-bridge cycling. While under tension, the muscle may lengthen, shorten or remain the same. Though the term \'contraction\' implies shortening, when referring to the muscular system it means muscle fibers generating tension with the help of motor neurons (the terms twitch tension, twitch force and fiber contraction are also used). Locomotion in most animals is possible only through the repeated contraction of many muscles at the correct times. Contraction is controlled by the central nervous system (CNS), which comprises the brain and spinal cord. Voluntary muscle contractions are initiated in the brain, while the spinal cord initiates involuntary reflexes.
Tags: Muscle contraction Status: private_owner_approval
Created: March 16, 2009, 6:21 pm

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HIV (Human immunodeficiency virus )
HIV structure and infection related videos. Wikipedia text: Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that can lead to acquired immunodeficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. Previous names for the virus include human T-lymphotropic virus-III (HTLV-III), lymphadenopathy-associated virus (LAV), and AIDS-associated retrovirus (ARV).[1][2] Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. The four major routes of transmission are unprotected sexual intercourse, contaminated needles, breast milk, and transmission from an infected mother to her baby at birth (Vertical transmission). Screening of blood products for HIV has largely eliminated transmission through blood transfusions or infected blood products in the developed world.
Tags: hiv Status: public
Created: March 18, 2009, 2:45 pm

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Actin Polymerization
Actin Polymerization related videos. Actin is a globular, roughly 42-kDa protein found in all eukaryotic cells (the only known exception being nematode sperm) where it may be present at concentrations of over 100 μM. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans. It is the monomeric subunit of microfilaments, one of the three major components of the cytoskeleton, and of thin filaments, which are part of the contractile apparatus in muscle cells. Thus, actin participates in many important cellular functions, including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. Text Reff: Wikipedia
Tags: Actin Polymerization Status: private_owner_approval
Created: March 26, 2009, 1:48 pm

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